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Analytical work also continued on determining the historical

European legislation has brought in a simple classification according to incidence of reported ADRs. These SPCs have all the legally required information about drugs marketed by companies within the Association of the British Pharmaceutical Industry (ABPI), which covers the majority of those manufacturing drugs you will use. The European classification is presented as percentage probabilities of developing an ADR and is shown in table below..

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Withhold LENVIMA for development of grade 3 cardiac dysfunction until improvement to grade 0 side effects of steroids, 1, or baseline. Resume at reduced dose or discontinue based on severity and persistence of cardiac dysfunction. Discontinue for grade 4 cardiac dysfunction.

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